Additional file 7 of BAX activation in mouse retinal ganglion cells occurs in two temporally and mechanistically distinct steps

Additional file 7: Supplemental Figure S5. qPCR data for pJUN and p53-associated gene expression comparing 1 day post optic nerve crush and 1 day post intravitreal injection of PF573228. (A) Relative change in transcript abundance for genes regulated by pJUN. (B) Relative change in transcript abundance for genes regulated by p53. The relative change reflects the difference between treated and contralateral eyes for each mouse examined (n=3 experimental replicates of 4 pooled retinas per treatment group). No statistical difference was noted between DMSO and PF573228-injected eyes (t-test comparison of means), while ONC induced significant accumulation of each transcript (ANOVA, * P