Additional file 2 of CTGF promotes the repair and regeneration of alveoli after acute lung injury by promoting the proliferation of subpopulation of AEC2s

Additional file 2: Fig. S2. Dose effect of CTGF and mouse pulmonary fibrosis. (A) Masson staining was observed in lung tissue after 7 days of continuous administration of 20 ug/kg CTGF, no obvious fiber staining was found in lung tissue. (B) After continuous administration of 100 ug/kg CTGF for 7 days, there was a small amount of fiber deposition in the alveolar septum (black arrow indicates fiber deposition). (C) Significant pulmonary fibrosis was observed after 7 days of continuous administration of 200ug/kg CTGF. Scale bar, 200 μm