Additional file 6 of Abnormal DNA methylation analysis of leucine-rich glioma-inactivated 1 antibody encephalitis reveals novel methylation-driven genes related to prognostic and clinical features

Additional file 6: Fig. S6. The expression profiles of microRNAs in exosome and their potential functionality. NTA analysis the size of EVs (A), EV concentration (B), the concentration of particle within the diameter 50–150nm (C), particle size and concentration in plasma (D and E). (F) A heat map representing discrepant microRNA expression values in plasma exosome of LGI1 encephalitis patients compared with those of healthy control. (G) and (H) KEGG pathways for 38 significant upregulated exo-microRNAs and 33 downregulated exo-microRNAs. (I) and (J) BP enrichment for 38 significant upregulated exo-microRNAs and 33 downregulated exo-microRNAs. (K) and (L) MF enrichment for 38 significant upregulated exo-microRNAs and 33 downregulated exo-microRNAs. LGI1-E, LGI1 encephalitis; ND, normal donor.