Additional file 1 of Crosstalk between 5-methylcytosine and N6-methyladenosine machinery defines disease progression, therapeutic response and pharmacogenomic landscape in hepatocellular carcinoma

Additional file 1 of Crosstalk between 5-methylcytosine and N6-methyladenosine machinery defines disease progression, therapeutic response and pharmacogenomic landscape in hepatocellular carcinoma

Additional file 1: Supplementary figure 1. Landscape of the expression levels and genetic alterations of 5mC/m6A regulators across 33 cancer types. (A) Gene expression profiling of 5mC/m6A regulators across pan-cancer. For a given 5mC/m6A regulator in each cancer type, the median expression value is...

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Hauptverfasser: Tian, Yu, Xiao, Haijuan, Yang, Yanhui, Zhang, Pingping, Yuan, Jiahui, Zhang, Wei, Chen, Lijie, Fan, Yibao, Zhang, Jinze, Cheng, Huan, Deng, Tingwei, Yang, Lin, Wang, Weiwei, Chen, Guoyong, Wang, Peiqin, Gong, Peng, Niu, Xing, Zhang, Xianbin
Format: Bild
Sprache:eng
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FOS: Biological sciences
Genetics
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Zusammenfassung:Additional file 1: Supplementary figure 1. Landscape of the expression levels and genetic alterations of 5mC/m6A regulators across 33 cancer types. (A) Gene expression profiling of 5mC/m6A regulators across pan-cancer. For a given 5mC/m6A regulator in each cancer type, the median expression value is shown. (B, C) Spearman correlations of CNVs with transcript levels of 5mC/m6A regulators in pan-cancer, reflecting the gene expression significantly affected by CNVs. (D, E) Pie chart for heterozygous and homozygous CNVs of 5mC/m6A regulators across cancer types.
DOI:10.6084/m9.figshare.22607189