Additional file 3 of Mitochondrial protective effects caused by the administration of mefenamic acid in sepsis

Additional file 3: Figure S3. Mefenamic acid decreases plasma cytokines levels in septic animals. Sepsis was induced by cecal ligation and perforation and mefenamic acid (10, 30 and 50 mg/kg) was administered immediately after sepsis induction. Twenty-four hours after rats were euthanized and the blood was drawn to the of A IL-1β, B IL-18 and C TNF-α plasma levels. Data are presented as mean ± SEM, with the statistical difference calculated using the one-way ANOVA test followed by Tukey's post hoc test. *p < 0.05 vs Sham + saline and #p < 0.05 vs CLP + saline. n = 8 per group.