Maximum tolerated dose and dose limiting toxicity of CDIM9

Maximum tolerated dose and dose limiting toxicity of CDIM9

Copyright information:Taken from "1,1-Bis(3'-indolyl)-1-(-biphenyl)methane inhibits basal-like breast cancer growth in athymic nude mice"http://breast-cancer-research.com/content/9/4/R56Breast cancer research : BCR 2007;9(4):R56-R56.Published online 31 Aug 2007PMCID:PMC2206732. Kaplan...

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Hauptverfasser: Yunpeng Su, Vanderlaag, Kathryn, Ireland, Courtney, Ortiz, Janelle, Grage, Henry, Safe, Stephen, Frankel, Arthur E
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Sprache:eng
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Zusammenfassung:Copyright information:Taken from "1,1-Bis(3'-indolyl)-1-(-biphenyl)methane inhibits basal-like breast cancer growth in athymic nude mice"http://breast-cancer-research.com/content/9/4/R56Breast cancer research : BCR 2007;9(4):R56-R56.Published online 31 Aug 2007PMCID:PMC2206732. Kaplan-Meier curves for 10 BalB/c mice (age 4 to 6 weeks) injected intraperitoneally (i.p.) with CDIM9 daily for a total of 35 doses. Hematoxylin and eosin staining of kidney and liver harvested from animals treated with 160 mg/kg per day CDIM9 for 12 days and after animals had recovered from treatment. Arrows indicated the tubular vacuolization (kidney) and steatosis (liver). CDIM9, 1,1-bis (3'-indolyl)-1-(p-biphenyl) methane.
DOI:10.6084/m9.figshare.20839