Additional file 1 of Sporadic Creutzfeldt-Jakob disease VM1: phenotypic and molecular characterization of a novel subtype of human prion disease

Additional file 1: Figure S1. Representative MR images. A1–A3: Patient #4, Spain, at 6 months of onset of symptoms. B1–B3: Patient #5, Italy, at 9 months of onset of symptoms. Diffusion weighted images of both patients reveal cortical hyperintensities, in patient 4 (A1–A3) particularly affecting the right parieto-occipital lobes, and in patient 5 (B1–B3) involving mostly the temporal, frontal, parietal and occipital lobes, predominantly of the left brain hemisphere. Basal ganglia do not show hyperintensities. A similar pattern was observed in the other patients where MRI was performed.