Additional file 2 of Altered macronutrient composition and genetics influence the complex transcriptional network associated with adiposity in the Collaborative Cross

Additional file 2: Supplementary Table 1. All genes significantly correlated with post-diet body fat % (2,552). Supplementary Table 2. Significant correlations between phenotypes and the top 30 genes with expression levels most strongly correlated with post-diet BF%. Supplementary Table 3. All genes...

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Hauptverfasser: Yam, Phoebe, VerHague, Melissa, Albright, Jody, Gertz, Erik, Pardo-Manuel de Villena, Fernando, Bennett, Brian J.
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Sprache:eng
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Zusammenfassung:Additional file 2: Supplementary Table 1. All genes significantly correlated with post-diet body fat % (2,552). Supplementary Table 2. Significant correlations between phenotypes and the top 30 genes with expression levels most strongly correlated with post-diet BF%. Supplementary Table 3. All genes with significant differential expression by diet (1,344). Supplementary Table 4. Genes differentially expressed by diet in the CC were significantly enriched for 20 KEGG pathways and 187 GO terms. Supplementary Table 5. All genes with significant differential expression by strain (9,436). Supplementary Table 6. Genes differentially expressed by strain in the CC were significantly enriched for 13 KEGG pathways and 163 GO terms. Supplementary Table 7. 65 DE genes by diet associated with obesity traits in humans are also significantly correlated with body fat %. Supplementary Table 8. 431 DE genes by strain associated with obesity traits in humans are also significantly correlated with body fat %. Supplementary Table 9. Module gene assignments. Supplementary Table 10. Spearman’s correlations between module eigengenes (MEs) and phenotypic traits. Supplementary Table 11. All significant enrichments for magenta, red, and yellow modules. Supplementary Table 12. Population of mice used in microarray analysis.
DOI:10.6084/m9.figshare.20461938