BoolODE Simulated Time Series with single gene KO

BoolODE was designed to simulate single-cell expression data sets on the basis of a network of gene-gene interactions (Pratapa et al., 2020). To simulate data sets with gene KOs, the simulations were allowed to run for 101 time points, at which point a gene’s expression value was set to zero and was...

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1. Verfasser: Erbe, Rossin
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Sprache:eng
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Zusammenfassung:BoolODE was designed to simulate single-cell expression data sets on the basis of a network of gene-gene interactions (Pratapa et al., 2020). To simulate data sets with gene KOs, the simulations were allowed to run for 101 time points, at which point a gene’s expression value was set to zero and was again set to zero on each future iteration, mimicking a KO gene.
DOI:10.6084/m9.figshare.20425467