Additional file 9 of Distinct cell type-specific protein signatures in GRN and MAPT genetic subtypes of frontotemporal dementia

Additional file 9 Comparison of protein effect sizes related to immune processes, metabolism, and mitochondria demonstrates that these are most affected in FTD-GRN. (A) Effect size plot comparing differentially expressed proteins from the ‘Metabolism’ GO group in FTD-GRN with FTD-MAPT. (B) Effect size plot comparing differentially expressed proteins from the ‘Immune’ GO group in FTD-GRN with FTD-MAPT. (C) Effect size plot comparing differentially expressed proteins from the ‘Mitochondria’ GO group in FTD-GRN with FTD-MAPT. Comparisons shows that, though (a portion of) proteins are affected in the other FTD subtype as well, these processes seem to be most affected in FTD-GRN. d; statistical effect size SAM analysis.