Additional file 1 of Lasmiditan and 5-Hydroxytryptamine in the rat trigeminal system; expression, release and interactions with 5-HT1 receptors

Additional file 1: Supplementary Figure 1. Involvement of the 5-HT1B and 5-HT1D receptors in the effect of Lasmiditan. Before the addition of 30 μM Lasmiditan, 300 nM of GR127935, a 5HT1B/5HT1D blocker was added to the TG which subsequently stimulated with 60 mM KCl (K+). Data are shown as mean ± SEM with * p>0.05, from the paired Student’s T-test being depicted in the graph.