Additional file 5 of TAGLN mediated stiffness-regulated ovarian cancer progression via RhoA/ROCK pathway

Additional file 5: Supplementary Figure 5. TAGLN expression correlated with substrates stiffness. (A) Transcriptomic profiling of SK-OV-3 cells cultured on soft (0.25 kPa) or stiff (40 kPa) PA gels. The heatmap shows genes upregulated in SK-OV-3 cells cultured on stiff (40 kPa) PA gels compared to s...

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Hauptverfasser:	Wei, Xiao, Lou, Hua, Zhou, Dongchen, Jia, Yijuan, Li, Huayi, Huang, Quanfu, Ma, Jingjing, Yang, Zongyuan, Sun, Chaoyang, Meng, Yunchong, Xu, Sen, Yang, Xin, Li, Xiaoting, Ji, Teng, Guo, Zhongzhen, Gao, Qinglei
Format:	Bild
Sprache:	eng
Schlagworte:	Biochemistry Biological Sciences not elsewhere classified Biophysics Cancer Chemical Sciences not elsewhere classified FOS: Biological sciences Genetics Microbiology Molecular Biology Physical Sciences not elsewhere classified
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Zusammenfassung:	Additional file 5: Supplementary Figure 5. TAGLN expression correlated with substrates stiffness. (A) Transcriptomic profiling of SK-OV-3 cells cultured on soft (0.25 kPa) or stiff (40 kPa) PA gels. The heatmap shows genes upregulated in SK-OV-3 cells cultured on stiff (40 kPa) PA gels compared to soft (0.25 kPa) PA gels. Green or red in the heat map indicate genes expression that was relatively low or high, respectively. (B-C) Relative TAGLN (B), THBS1, OXTR (C) mRNA expression levels of SK-OV-3 and ES-2 cells cultured on substrates of different stiffness determined by quantitative PCR
DOI:	10.6084/m9.figshare.16641844