Supplemantal Figure 1. LC-MS/MS determination of DOC, corticosterone and aldosterone over time in three ASD patients after discontinuation of fludrocortisone treatment

Supplemantal Figure 1. LC-MS/MS determination of DOC, corticosterone and aldosterone over time in three ASD patients after discontinuation of fludrocortisone treatment

Supplemantal Figure 1. LC-MS/MS determination of DOC, corticosterone and aldosterone over time in three ASD patients after discontinuation of fludrocortisone treatment. Compared to control individuals (open circles), steroid measurements of F2P1 (A; upper panel, black squares), F3P1 (B; middle panel...

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Hauptverfasser: Gurpinar Tosun, Busra, Kendir Demirkol, Yasemin, Seven Menevse, Tuba, Kaygusuz, Sare Betul, Ozbek, Mehmet Nuri, Altıncık, Selda Ayça, Mamadova, Jamala, Cayir, Atilla, Doger, Esra, Bayramoglu, Elvan, Nalbantoğlu, Özlem, Yesiltepe Mutlu, Gul Yesiltepe, Aghayev, AghaRza, Turan, Serap, Bereket, Abdullah, Guran, Tulay
Format: Bild
Sprache:eng
Schlagworte:
Endocrinology
FOS: Clinical medicine
Paediatrics
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Zusammenfassung:Supplemantal Figure 1. LC-MS/MS determination of DOC, corticosterone and aldosterone over time in three ASD patients after discontinuation of fludrocortisone treatment. Compared to control individuals (open circles), steroid measurements of F2P1 (A; upper panel, black squares), F3P1 (B; middle panel, black circles), and F4P2 (C; lower panel, black triangles) are presented. P values of compared measurements are shown in the upper left corner of each graph. Corticosterone and DOC were higher and aldosterone concentrations were low/normal in patients after their treatment could be discontinued which suggests ongoing insufficiency of aldosterone synthase.
DOI:10.6084/m9.figshare.15070548