Protein–protein interactions of transcription activators

Copyright information:Taken from "Transcriptional activators in yeast"Nucleic Acids Research 2006;34(3):955-967.Published online 7 Feb 2006PMCID:PMC1361621.© The Author 2006. Published by Oxford University Press. All rights reserved () This protein interaction network shows the activators (red) and the proteins interacting with at least two activators. Proteins involved in transcription are indicated by a diamond shape and the activation strength (bGal and LTH combined) is reflected by the node size. Individual protein names can be identified in the online version of this figure. () Protein–protein interactions of activators and control groups with other proteins involved in transcription (P-GO term ‘transcription’). Physical, binary protein interaction data from the MIPS database () were used. The right three columns include indirect interactions involving a bridging protein (indicated by ‘+1’) between the activator and the transcription protein. () Percentage of proteins interacting with components of protein complexes involved in transcription. Only high-throughput derived protein complex data from the MIPS database were considered.