Additional file 2 of Iron overload adversely effects bone marrow haematogenesis via SIRT-SOD2-mROS in a process ameliorated by curcumin

Additional file 2: Fig. S3. Iron overload could cause bone marrow damage in vivo. A—The cell viability of mononuclear cells in the bone marrow of the iron-overloaded mice decreased. B and C—LIP (B) and mROS (C) levels increased in iron-overloaded mice. D and E—SOD2 (D) and SIRT3 (E) activities decre...

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Hauptverfasser: Zhou, Shujuan, Sun, Lan, Shanhu Qian, Yongyong Ma, Ruye Ma, Yuqing Dong, Yifen Shi, Songfu Jiang, Haige Ye, Zhijian Shen, Shenghui Zhang, Jianping Shen, Yu, Kang, Siqian Wang
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Sprache:eng
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Zusammenfassung:Additional file 2: Fig. S3. Iron overload could cause bone marrow damage in vivo. A—The cell viability of mononuclear cells in the bone marrow of the iron-overloaded mice decreased. B and C—LIP (B) and mROS (C) levels increased in iron-overloaded mice. D and E—SOD2 (D) and SIRT3 (E) activities decreased in iron-overloaded mice. F—Iron-overloaded mice showed decreased Hb levels, PLT counts, and WBC counts in their peripheral blood. The values are presented as the means ± SEM, **p
DOI:10.6084/m9.figshare.13566156