Additional file 6 of Estrogen-related receptor alpha directly binds to p53 and cooperatively controls colon cancer growth through the regulation of mitochondrial biogenesis and function

Additional file 6: Figure S6. Related to Fig. 6. A Overall p53 mutational spectrum was performed for 37 colon cancer patients. B IB analysis was conducted using anti-p53 and anti-GAPDH in HCT-116p53+/+ and HCT-116p53-/- cells. Images show the GFP signal. C A random toxicity study was performed. All animals were euthanized and liver and spleen were extracted and weighed (n = 4). D At the end of the treatment period, all animals were euthanized and liver and spleen were extracted and weighed (n = 7).