K18-hACE2 mice develop respiratory disease resembling severe COVID-19

A study describing the development of COVID-19 transgenic mice model showing it usefulness in elucidating COVID-19 pathogenesis and testing of countermeasures.

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Hauptverfasser: Kwe, Claude Yinda, Port, Julia R., Bushmaker, Trenton, Owusu, Irene Offei, Avanzato, Victoria, Fischer, Robert J., Schulz, Jonathan E., Myndi G. Holbrook, Hebner, Madison J., Rosenke, Rebecca, Thomas, Tina, Marzi, Andrea, Best, Sonja M., Wit, Emmie De, Shaia, Carl, Doremalen, Neeltje Van, Munster, Vincent J.
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Sprache:eng
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Zusammenfassung:A study describing the development of COVID-19 transgenic mice model showing it usefulness in elucidating COVID-19 pathogenesis and testing of countermeasures.
DOI:10.6084/m9.figshare.12836813