Additional file 2 of P2RX7 inhibitor suppresses exosome secretion and disease phenotype in P301S tau transgenic mice

Additional file 2: Supplementary Fig. S2. PLA signals between Alz50 and Tsg/Hgs in hippocampus. A. Epi-fluorescence microscopic images of Tsg101 and Alz50 staining in the DG, CA1 and CA3 of hippocampal region of P301S mice ± GSK1482160 treatment and wild-type mice. Original images were captured at 20× objective. B. Representative laser-scanning confocal microscopic images of PLA signals between Hgs and Alz50 at CA1 and CA3 of hippocampus (red) with Dapi counterstaining for nucleus (blue). Original images were captured at 63× oil immersion objective.