Additional file 1 of Th17 cells inhibit CD8+ T cell migration by systematically downregulating CXCR3 expression via IL-17A/STAT3 in advanced-stage colorectal cancer patients

Additional file 1 of Th17 cells inhibit CD8+ T cell migration by systematically downregulating CXCR3 expression via IL-17A/STAT3 in advanced-stage colorectal cancer patients

Additional file 1: Table S1. Primers used in this study. Figure S1. The migratory ability of CD8+ T cells to CXCL10 depends on CXCR3 expression. Figure S2. The expression of CXCR3 ligands were unchanged after IL-17A stimulation. Figure S3. High expression levels of P-STAT3 in CD8+ T cells of advance...

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Hauptverfasser: Wang, Dan, Yu, Weina, Lian, Jingyao, Wu, Qian, Liu, Shasha, Yang, Li, Li, Feng, Huang, Lan, Chen, Xinfeng, Zhang, Zhen, Li, Aitian, Liu, Jinbo, Sun, Zhenqiang, Wang, Junxia, Yuan, Weitang, Zhang, Yi
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Sprache:eng
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Biochemistry
Biological Sciences not elsewhere classified
Biotechnology
Cancer
Cell Biology
Chemical Sciences not elsewhere classified
Developmental Biology
FOS: Biological sciences
FOS: Clinical medicine
Genetics
Immunology
Medicine
Molecular Biology
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Zusammenfassung:Additional file 1: Table S1. Primers used in this study. Figure S1. The migratory ability of CD8+ T cells to CXCL10 depends on CXCR3 expression. Figure S2. The expression of CXCR3 ligands were unchanged after IL-17A stimulation. Figure S3. High expression levels of P-STAT3 in CD8+ T cells of advanced-stage CRC. Figure S4. IL-17A is predominantly secreted by CD4+ T cells from PB of CRC patients. Figure S5. The positive efficiency of enriched Th17 cells. Figure S6. CXCR3 is predominantly expressed in the stromal CD8+ T cells of tumor tissues, and IL-17A is mainly secreted by CD4+ T cells
DOI:10.6084/m9.figshare.12441452