MOESM7 of Loss of amyloid precursor protein exacerbates early inflammation in Niemann-Pick disease type C
Additional file 7: Figure S7. Loss of APP function results in the exacerbation of DEGs functionally related to the activation of T-lymphocytes in Npc1-/-/App-/- mouse cerebella. All differentially expressed genes (DEGs) are localized to their sub-cellular location. All plotted DEGs meet the signific...
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creator | Shin, Samuel Shin, Alexandra Mayagoitia, Karina Siebold, Lorraine Rubini, Marsilio Wilson, Christopher Bellinger, Denise Soriano, Salvador |
description | Additional file 7: Figure S7. Loss of APP function results in the exacerbation of DEGs functionally related to the activation of T-lymphocytes in Npc1-/-/App-/- mouse cerebella. All differentially expressed genes (DEGs) are localized to their sub-cellular location. All plotted DEGs meet the significance cutoff of fold-change (absolute FC > 1.5) and p-value (p < 0.05). *Duplicate identifiers used for the same gene. A detailed key for IPA molecular shape, color, and interaction is provided in Fig. 2. |
doi_str_mv | 10.6084/m9.figshare.11393529 |
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Loss of APP function results in the exacerbation of DEGs functionally related to the activation of T-lymphocytes in Npc1-/-/App-/- mouse cerebella. All differentially expressed genes (DEGs) are localized to their sub-cellular location. All plotted DEGs meet the significance cutoff of fold-change (absolute FC > 1.5) and p-value (p < 0.05). *Duplicate identifiers used for the same gene. 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Loss of APP function results in the exacerbation of DEGs functionally related to the activation of T-lymphocytes in Npc1-/-/App-/- mouse cerebella. All differentially expressed genes (DEGs) are localized to their sub-cellular location. All plotted DEGs meet the significance cutoff of fold-change (absolute FC > 1.5) and p-value (p < 0.05). *Duplicate identifiers used for the same gene. A detailed key for IPA molecular shape, color, and interaction is provided in Fig. 2.</description><subject>Biochemistry</subject><subject>Cell Biology</subject><subject>Developmental Biology</subject><subject>FOS: Biological sciences</subject><subject>FOS: Health sciences</subject><subject>Genetics</subject><subject>Infectious Diseases</subject><subject>Medicine</subject><subject>Molecular Biology</subject><subject>Neuroscience</subject><subject>Physiology</subject><fulltext>true</fulltext><rsrctype>image</rsrctype><creationdate>2019</creationdate><recordtype>image</recordtype><sourceid>PQ8</sourceid><recordid>eNqdjjsOwjAQBd1QIOAGFHsBQkLCJzUCUfCToLeWZAMrYjuyjYRvTyLBBajmvWKkEWKcxNEiXmVTlUcV390DLUVJkubpfJb3BR9Om8thCaaCvXGuI6pQGy6hsVS8rDO2XcYTa6A3FmRv6MkBoa0DsK5qVAo9G90eODIp1Hpy5uIJJTtCR-BDQ7Aeil6FtaPRlwORbTfX9W5SoseCPcnGskIbZBLLrliqXP6K5a84_VP7AAnoVUU</recordid><startdate>20191218</startdate><enddate>20191218</enddate><creator>Shin, Samuel</creator><creator>Shin, Alexandra</creator><creator>Mayagoitia, Karina</creator><creator>Siebold, Lorraine</creator><creator>Rubini, Marsilio</creator><creator>Wilson, Christopher</creator><creator>Bellinger, Denise</creator><creator>Soriano, Salvador</creator><general>figshare</general><scope>DYCCY</scope><scope>PQ8</scope></search><sort><creationdate>20191218</creationdate><title>MOESM7 of Loss of amyloid precursor protein exacerbates early inflammation in Niemann-Pick disease type C</title><author>Shin, Samuel ; Shin, Alexandra ; Mayagoitia, Karina ; Siebold, Lorraine ; Rubini, Marsilio ; Wilson, Christopher ; Bellinger, Denise ; Soriano, Salvador</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-datacite_primary_10_6084_m9_figshare_113935293</frbrgroupid><rsrctype>images</rsrctype><prefilter>images</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Biochemistry</topic><topic>Cell Biology</topic><topic>Developmental Biology</topic><topic>FOS: Biological sciences</topic><topic>FOS: Health sciences</topic><topic>Genetics</topic><topic>Infectious Diseases</topic><topic>Medicine</topic><topic>Molecular Biology</topic><topic>Neuroscience</topic><topic>Physiology</topic><toplevel>online_resources</toplevel><creatorcontrib>Shin, Samuel</creatorcontrib><creatorcontrib>Shin, Alexandra</creatorcontrib><creatorcontrib>Mayagoitia, Karina</creatorcontrib><creatorcontrib>Siebold, Lorraine</creatorcontrib><creatorcontrib>Rubini, Marsilio</creatorcontrib><creatorcontrib>Wilson, Christopher</creatorcontrib><creatorcontrib>Bellinger, Denise</creatorcontrib><creatorcontrib>Soriano, Salvador</creatorcontrib><collection>DataCite (Open Access)</collection><collection>DataCite</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Shin, Samuel</au><au>Shin, Alexandra</au><au>Mayagoitia, Karina</au><au>Siebold, Lorraine</au><au>Rubini, Marsilio</au><au>Wilson, Christopher</au><au>Bellinger, Denise</au><au>Soriano, Salvador</au><format>book</format><genre>unknown</genre><ristype>GEN</ristype><title>MOESM7 of Loss of amyloid precursor protein exacerbates early inflammation in Niemann-Pick disease type C</title><date>2019-12-18</date><risdate>2019</risdate><abstract>Additional file 7: Figure S7. Loss of APP function results in the exacerbation of DEGs functionally related to the activation of T-lymphocytes in Npc1-/-/App-/- mouse cerebella. All differentially expressed genes (DEGs) are localized to their sub-cellular location. All plotted DEGs meet the significance cutoff of fold-change (absolute FC > 1.5) and p-value (p < 0.05). *Duplicate identifiers used for the same gene. A detailed key for IPA molecular shape, color, and interaction is provided in Fig. 2.</abstract><pub>figshare</pub><doi>10.6084/m9.figshare.11393529</doi><oa>free_for_read</oa></addata></record> |
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subjects | Biochemistry Cell Biology Developmental Biology FOS: Biological sciences FOS: Health sciences Genetics Infectious Diseases Medicine Molecular Biology Neuroscience Physiology |
title | MOESM7 of Loss of amyloid precursor protein exacerbates early inflammation in Niemann-Pick disease type C |
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