MOESM7 of Loss of amyloid precursor protein exacerbates early inflammation in Niemann-Pick disease type C

Additional file 7: Figure S7. Loss of APP function results in the exacerbation of DEGs functionally related to the activation of T-lymphocytes in Npc1-/-/App-/- mouse cerebella. All differentially expressed genes (DEGs) are localized to their sub-cellular location. All plotted DEGs meet the signific...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Shin, Samuel, Shin, Alexandra, Mayagoitia, Karina, Siebold, Lorraine, Rubini, Marsilio, Wilson, Christopher, Bellinger, Denise, Soriano, Salvador
Format: Bild
Sprache:eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator Shin, Samuel
Shin, Alexandra
Mayagoitia, Karina
Siebold, Lorraine
Rubini, Marsilio
Wilson, Christopher
Bellinger, Denise
Soriano, Salvador
description Additional file 7: Figure S7. Loss of APP function results in the exacerbation of DEGs functionally related to the activation of T-lymphocytes in Npc1-/-/App-/- mouse cerebella. All differentially expressed genes (DEGs) are localized to their sub-cellular location. All plotted DEGs meet the significance cutoff of fold-change (absolute FC > 1.5) and p-value (p < 0.05). *Duplicate identifiers used for the same gene. A detailed key for IPA molecular shape, color, and interaction is provided in Fig. 2.
doi_str_mv 10.6084/m9.figshare.11393529
format Image
fullrecord <record><control><sourceid>datacite_PQ8</sourceid><recordid>TN_cdi_datacite_primary_10_6084_m9_figshare_11393529</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>10_6084_m9_figshare_11393529</sourcerecordid><originalsourceid>FETCH-datacite_primary_10_6084_m9_figshare_113935293</originalsourceid><addsrcrecordid>eNqdjjsOwjAQBd1QIOAGFHsBQkLCJzUCUfCToLeWZAMrYjuyjYRvTyLBBajmvWKkEWKcxNEiXmVTlUcV390DLUVJkubpfJb3BR9Om8thCaaCvXGuI6pQGy6hsVS8rDO2XcYTa6A3FmRv6MkBoa0DsK5qVAo9G90eODIp1Hpy5uIJJTtCR-BDQ7Aeil6FtaPRlwORbTfX9W5SoseCPcnGskIbZBLLrliqXP6K5a84_VP7AAnoVUU</addsrcrecordid><sourcetype>Publisher</sourcetype><iscdi>true</iscdi><recordtype>image</recordtype></control><display><type>image</type><title>MOESM7 of Loss of amyloid precursor protein exacerbates early inflammation in Niemann-Pick disease type C</title><source>DataCite</source><creator>Shin, Samuel ; Shin, Alexandra ; Mayagoitia, Karina ; Siebold, Lorraine ; Rubini, Marsilio ; Wilson, Christopher ; Bellinger, Denise ; Soriano, Salvador</creator><creatorcontrib>Shin, Samuel ; Shin, Alexandra ; Mayagoitia, Karina ; Siebold, Lorraine ; Rubini, Marsilio ; Wilson, Christopher ; Bellinger, Denise ; Soriano, Salvador</creatorcontrib><description>Additional file 7: Figure S7. Loss of APP function results in the exacerbation of DEGs functionally related to the activation of T-lymphocytes in Npc1-/-/App-/- mouse cerebella. All differentially expressed genes (DEGs) are localized to their sub-cellular location. All plotted DEGs meet the significance cutoff of fold-change (absolute FC &gt; 1.5) and p-value (p &lt; 0.05). *Duplicate identifiers used for the same gene. A detailed key for IPA molecular shape, color, and interaction is provided in Fig. 2.</description><identifier>DOI: 10.6084/m9.figshare.11393529</identifier><language>eng</language><publisher>figshare</publisher><subject>Biochemistry ; Cell Biology ; Developmental Biology ; FOS: Biological sciences ; FOS: Health sciences ; Genetics ; Infectious Diseases ; Medicine ; Molecular Biology ; Neuroscience ; Physiology</subject><creationdate>2019</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>780,1894</link.rule.ids><linktorsrc>$$Uhttps://commons.datacite.org/doi.org/10.6084/m9.figshare.11393529$$EView_record_in_DataCite.org$$FView_record_in_$$GDataCite.org$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Shin, Samuel</creatorcontrib><creatorcontrib>Shin, Alexandra</creatorcontrib><creatorcontrib>Mayagoitia, Karina</creatorcontrib><creatorcontrib>Siebold, Lorraine</creatorcontrib><creatorcontrib>Rubini, Marsilio</creatorcontrib><creatorcontrib>Wilson, Christopher</creatorcontrib><creatorcontrib>Bellinger, Denise</creatorcontrib><creatorcontrib>Soriano, Salvador</creatorcontrib><title>MOESM7 of Loss of amyloid precursor protein exacerbates early inflammation in Niemann-Pick disease type C</title><description>Additional file 7: Figure S7. Loss of APP function results in the exacerbation of DEGs functionally related to the activation of T-lymphocytes in Npc1-/-/App-/- mouse cerebella. All differentially expressed genes (DEGs) are localized to their sub-cellular location. All plotted DEGs meet the significance cutoff of fold-change (absolute FC &gt; 1.5) and p-value (p &lt; 0.05). *Duplicate identifiers used for the same gene. A detailed key for IPA molecular shape, color, and interaction is provided in Fig. 2.</description><subject>Biochemistry</subject><subject>Cell Biology</subject><subject>Developmental Biology</subject><subject>FOS: Biological sciences</subject><subject>FOS: Health sciences</subject><subject>Genetics</subject><subject>Infectious Diseases</subject><subject>Medicine</subject><subject>Molecular Biology</subject><subject>Neuroscience</subject><subject>Physiology</subject><fulltext>true</fulltext><rsrctype>image</rsrctype><creationdate>2019</creationdate><recordtype>image</recordtype><sourceid>PQ8</sourceid><recordid>eNqdjjsOwjAQBd1QIOAGFHsBQkLCJzUCUfCToLeWZAMrYjuyjYRvTyLBBajmvWKkEWKcxNEiXmVTlUcV390DLUVJkubpfJb3BR9Om8thCaaCvXGuI6pQGy6hsVS8rDO2XcYTa6A3FmRv6MkBoa0DsK5qVAo9G90eODIp1Hpy5uIJJTtCR-BDQ7Aeil6FtaPRlwORbTfX9W5SoseCPcnGskIbZBLLrliqXP6K5a84_VP7AAnoVUU</recordid><startdate>20191218</startdate><enddate>20191218</enddate><creator>Shin, Samuel</creator><creator>Shin, Alexandra</creator><creator>Mayagoitia, Karina</creator><creator>Siebold, Lorraine</creator><creator>Rubini, Marsilio</creator><creator>Wilson, Christopher</creator><creator>Bellinger, Denise</creator><creator>Soriano, Salvador</creator><general>figshare</general><scope>DYCCY</scope><scope>PQ8</scope></search><sort><creationdate>20191218</creationdate><title>MOESM7 of Loss of amyloid precursor protein exacerbates early inflammation in Niemann-Pick disease type C</title><author>Shin, Samuel ; Shin, Alexandra ; Mayagoitia, Karina ; Siebold, Lorraine ; Rubini, Marsilio ; Wilson, Christopher ; Bellinger, Denise ; Soriano, Salvador</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-datacite_primary_10_6084_m9_figshare_113935293</frbrgroupid><rsrctype>images</rsrctype><prefilter>images</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Biochemistry</topic><topic>Cell Biology</topic><topic>Developmental Biology</topic><topic>FOS: Biological sciences</topic><topic>FOS: Health sciences</topic><topic>Genetics</topic><topic>Infectious Diseases</topic><topic>Medicine</topic><topic>Molecular Biology</topic><topic>Neuroscience</topic><topic>Physiology</topic><toplevel>online_resources</toplevel><creatorcontrib>Shin, Samuel</creatorcontrib><creatorcontrib>Shin, Alexandra</creatorcontrib><creatorcontrib>Mayagoitia, Karina</creatorcontrib><creatorcontrib>Siebold, Lorraine</creatorcontrib><creatorcontrib>Rubini, Marsilio</creatorcontrib><creatorcontrib>Wilson, Christopher</creatorcontrib><creatorcontrib>Bellinger, Denise</creatorcontrib><creatorcontrib>Soriano, Salvador</creatorcontrib><collection>DataCite (Open Access)</collection><collection>DataCite</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Shin, Samuel</au><au>Shin, Alexandra</au><au>Mayagoitia, Karina</au><au>Siebold, Lorraine</au><au>Rubini, Marsilio</au><au>Wilson, Christopher</au><au>Bellinger, Denise</au><au>Soriano, Salvador</au><format>book</format><genre>unknown</genre><ristype>GEN</ristype><title>MOESM7 of Loss of amyloid precursor protein exacerbates early inflammation in Niemann-Pick disease type C</title><date>2019-12-18</date><risdate>2019</risdate><abstract>Additional file 7: Figure S7. Loss of APP function results in the exacerbation of DEGs functionally related to the activation of T-lymphocytes in Npc1-/-/App-/- mouse cerebella. All differentially expressed genes (DEGs) are localized to their sub-cellular location. All plotted DEGs meet the significance cutoff of fold-change (absolute FC &gt; 1.5) and p-value (p &lt; 0.05). *Duplicate identifiers used for the same gene. A detailed key for IPA molecular shape, color, and interaction is provided in Fig. 2.</abstract><pub>figshare</pub><doi>10.6084/m9.figshare.11393529</doi><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier DOI: 10.6084/m9.figshare.11393529
ispartof
issn
language eng
recordid cdi_datacite_primary_10_6084_m9_figshare_11393529
source DataCite
subjects Biochemistry
Cell Biology
Developmental Biology
FOS: Biological sciences
FOS: Health sciences
Genetics
Infectious Diseases
Medicine
Molecular Biology
Neuroscience
Physiology
title MOESM7 of Loss of amyloid precursor protein exacerbates early inflammation in Niemann-Pick disease type C
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-22T19%3A18%3A38IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-datacite_PQ8&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=unknown&rft.au=Shin,%20Samuel&rft.date=2019-12-18&rft_id=info:doi/10.6084/m9.figshare.11393529&rft_dat=%3Cdatacite_PQ8%3E10_6084_m9_figshare_11393529%3C/datacite_PQ8%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true