MOESM7 of Loss of amyloid precursor protein exacerbates early inflammation in Niemann-Pick disease type C

MOESM7 of Loss of amyloid precursor protein exacerbates early inflammation in Niemann-Pick disease type C

Additional file 7: Figure S7. Loss of APP function results in the exacerbation of DEGs functionally related to the activation of T-lymphocytes in Npc1-/-/App-/- mouse cerebella. All differentially expressed genes (DEGs) are localized to their sub-cellular location. All plotted DEGs meet the signific...

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Bibliographische Detailangaben
Hauptverfasser: Shin, Samuel, Shin, Alexandra, Mayagoitia, Karina, Siebold, Lorraine, Rubini, Marsilio, Wilson, Christopher, Bellinger, Denise, Soriano, Salvador
Format: Bild
Sprache:eng
Schlagworte:
Biochemistry
Cell Biology
Developmental Biology
FOS: Biological sciences
FOS: Health sciences
Genetics
Infectious Diseases
Medicine
Molecular Biology
Neuroscience
Physiology
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Zusammenfassung:Additional file 7: Figure S7. Loss of APP function results in the exacerbation of DEGs functionally related to the activation of T-lymphocytes in Npc1-/-/App-/- mouse cerebella. All differentially expressed genes (DEGs) are localized to their sub-cellular location. All plotted DEGs meet the significance cutoff of fold-change (absolute FC > 1.5) and p-value (p < 0.05). *Duplicate identifiers used for the same gene. A detailed key for IPA molecular shape, color, and interaction is provided in Fig. 2.
DOI:10.6084/m9.figshare.11393529