Disseminated apoptotic and nonapoptotic disseminated tumor cells

Copyright information:Taken from "Presence of apoptotic and nonapoptotic disseminated tumor cells reflects the response to neoadjuvant systemic therapy in breast cancer"Breast Cancer Research 2006;8(5):R60-R60.Published online 24 Oct 2006PMCID:PMC1779490. Nonapoptotic disseminated tumor cell (DTC) (detected by the APAAP kit method). Apoptotic DTC identified by M30 staining and morphological assessment (for example, membrane blebbing, nuclear shrinkage) (APAAP kit detection method). Apoptotic DTC identified by morphological assessment (nuclear shrinkage, cytokeratin inclusions) (DTC detected by a fluorescein-5-isothiocyanate-labeled anticytokeratin antibody). Apoptotic cell body without detectable amounts of chromatin.