MOESM4 of Immunogenicity of prostate cancer is augmented by BET bromodomain inhibition

Additional file 4: Figure S3. BET Bromodomain Inhibition Downregulates PD-L1 and Augments MHC I Expression in MC38OVA. A. Representative histograms of PD-L1 expression in MC38OVA cells treated with JQ1 and/or IFNγ gated on live cells. B. Summary flow cytometry data for A. N = 1 sample / iteration, r...

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Hauptverfasser:	Mao, Wendy, Ghasemzadeh, Ali, Freeman, Zachary T., Obradovic, Aleksandar, Chaimowitz, Matthew G., Nirschl, Thomas R., McKiernan, Emily, Srinivasan Yegnasubramanian, Drake, Charles G.
Format:	Video
Sprache:	eng
Schlagworte:	Biological Sciences not elsewhere classified Cancer Chemical Sciences not elsewhere classified FOS: Biological sciences FOS: Chemical sciences FOS: Clinical medicine Genetics Immunology Molecular Biology Physiology Virology
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Zusammenfassung:	Additional file 4: Figure S3. BET Bromodomain Inhibition Downregulates PD-L1 and Augments MHC I Expression in MC38OVA. A. Representative histograms of PD-L1 expression in MC38OVA cells treated with JQ1 and/or IFNγ gated on live cells. B. Summary flow cytometry data for A. N = 1 sample / iteration, repeated × 3. C. Representative histograms of H2KbDb expression in MC38OVA cells treated with JQ1 and/or IFNγ gated on live cells. D. Summary flow cytometry data for C. N = 1 sample / iteration, repeated × 3. * p
DOI:	10.6084/m9.figshare.10052933