MOESM2 of Congenital infection with atypical porcine pestivirus (APPV) is associated with disease and viral persistence

Additional file 2. Electron micrographs of the central nervous system of an affected piglet show severe lesions. (A) Separation and decompaction of myelin sheaths (white asterisk) as well as intraaxonal vacuole formation (x) in the cerebellar white matter, bar = 2.5 µm. (B) Axonal degeneration (black arrow), vacuole formation (x) and myelin balloons (black asterisk) in the medulla oblongata, bar = 2.5 µm. (C) Defects of the myelin lamellae characterized by disruption of lamellae (black arrowhead) and formation of myelin balloons (black asterisk) in the medulla oblongata, bar = 250 nm.