CIL:33951, Homo sapiens, endocrine-paracrine cell of prostate gland, basal cell of prostate epithelium, luminal cell of prostate epithelium, blood vessel endothelial cell, perineural cell, sheath cell, leukocyte, prostate stromal cell, smooth muscle cell of prostate. In Cell Image Library

Tissue section of human prostate containing adenocarcinoma that has been immunostained for the cell-surface antigen CD90. Nuclei are stained in blue.This image is part of a large collection of images generated from numerous specimens to characterize the distribution of CD90 in human prostate tissue. It was noted in Liu et al. (Am J Pathol 165 (2004) 1543-1556) that stromal fibromuscular cells associated with primary prostate cancer differ from stromal cells in benign prostate tissue by an increased level of expression of the cell activation molecule, CD90. A summary of the entire data set is provided below. Cell Type, % intense, % equivocal, % none, # assays, Atrophic glands:, 0, 0, 100, 11, Hyperplastic glands:, 0, 0, 100, 11, Normal glands:, 0, 0, 100, 11, Basal Epithelial Cells:, 0, 0, 100, 11, Stromal Endothelial Cells:, 70, 1, 29, 11, Stromal Fibromuscular Cells:, 15, 0, 85, 11, Stromal Nerve Sheath Cells:, 60, 2, 38, 11, Stromal Perineural Cells:, 0, 0, 100, 11, Gleason Pattern 3:, 0, 0, 100, 9, Gleason Pattern 4:, 0, 0, 100, 6, Gleason Pattern 5:, 0, 0, 100, 1 The table indicates the percent of each cell type with the indicated staining intensity. Staining intensity levels were classified as intense, equivocal (weak or very focal) or none. Not all of the cell types and staining patterns are visible in each image. This image is part of a large collection of immunohistochemistry images of cell-surface antigens generated by the SCGAP Urologic Epithelial Stem Cells (UESC) Project. The overall goal of the project is to characterize and isolate epithelial stem cell populations from two urologic organs, the prostate and bladder. Links are provided below for the UESC Project database, the entire human prostate immunostain summary, the CD90 immunostain summary, and information on the specimen that this image is from. Other images of CD90 human prostate immunostains are accessible following the group link.