Supporting data for "BS-virus-finder: virus integration calling using bisulfite-sequencing data"

Supporting data for "BS-virus-finder: virus integration calling using bisulfite-sequencing data"

DNA methylation plays a key role in regulating gene expression and carcinogenesis. Extant methylation bisulfite sequencing (BS) researches mainly focus on calling SNP, DMR, and ASM, instead of virus integration positions. We developed a new and easy-to-use software, named as BS-virus-finder (https:/...

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Bibliographische Detailangaben
Hauptverfasser: Bo, Li, Changduo, Gao, Pedersen NS Christian, Dongke, Fu, Fengping, Xu, Haixiao, Chen, Huangming, Yang, Jian, Wang, Jie, Bai, Kai, Xiong, Bolund Lars, Likai, Mao, Mengyao, Wang, Shancen, Zhao, Shengbin, Li, Shengjie, Gao, Song, Wu, Xiao, Zhao, Xiaohui, Zhao, Xuesong, Hu
Format: Dataset
Sprache:eng
Schlagworte:
bisulfite sequencing
carcinogenesis
Software
virus integration
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Beschreibung
Zusammenfassung:DNA methylation plays a key role in regulating gene expression and carcinogenesis. Extant methylation bisulfite sequencing (BS) researches mainly focus on calling SNP, DMR, and ASM, instead of virus integration positions. We developed a new and easy-to-use software, named as BS-virus-finder (https://github.com/BioInfoTools/BSVF), to detect viral integration breakpoints in whole human genomes. BS-virus-finder demonstrates moderate sensitivity and specificity, and is useful to be applied in epigenetic researches and to reveal the relationship between viral integration and DNA methylation. BS-virus-finder is the first software to detect virus by using bisulfite sequencing data.
DOI:10.5524/100377