Supplementary Data: Multimodal imaging reveals multiscale mechanical interplay in vertebral endplate microarchitecture during intervertebral disc loading

Data related to the publication "Multimodal imaging reveals multiscale mechanical interplay in vertebral endplate microarchitecture during intervertebral disc loading", Parmenter et al., 2024, https://www.biorxiv.org/content/10.1101/2024.08.19.608559v1Full methodology described in the above publication.Total data size = 41 GBData used for statistical analysis:sCT_DVC_stats_data.csv : Data used for statistical analysis shown in Fig. 3 and Fig. 4DIAD_stats_data.csv : Data used for statistical analysis shown in Fig. 6WAXD processing code:processing_folder_D-period.py : python code for measuring diffraction peak parametersctMapperGUI.py : python code for mapping WAXD parameters onto X-ray projection imageExample sCT and DVC dataset (sample 5):162365_2560xy_2160z_pag100_us2p5_8bit.tif : reconstructed sCT image of sample under 1 N preload, 13 GB, recommend opening in imageJ162366_2560xy_2160z_pag100_us2p5_8bit.tif : reconstructed sCT image of sample after 40 micron displacement, 13 GB, recommend opening in imageJ162365_caudal_mindist4p5_mesh.inp : mesh of caudal VEP used for creating the DVC pointcloud, ABAQUS input file162366_cranial_mindist4p5_mesh.inp : mesh of cranial VEP used for creating the DVC pointcloud, ABAQUS input file162365_caudal_pointcloud.txt : caudal VEP pointcloud for DVC162365_cranial_pointcloud.txt : cranial VEP pointcloud for DVCdvc_162365_caudal.disp : DVC displacement results for caudal VEP, output from iDVC executable, can visualise in Matlabdvc_162365_cranial.disp : DVC displacement results for caudal VEP, output from iDVC executable, can visualise in Matlabsample5_caudal_step1.csv : strain data for caudal endplate generated from disp filesample5_caudal_step1.csv : strain data for cranial endplate generated from disp filesample5_force_readout.xlsx : force, displacement, time data readout from the mechanical testing rig during the experimentsample5BinaryROIs.zip : binary images of regions used for microarchitecture analysissample5ROImsvalues.xlsx : microarchitecture values for regions of interestExample correlative sCT and WAXD dataset (sample 16):17565_2560xy_2160z_us1_8bit.tif : reconstructed sCT image, 13 GB, recommend opening in imageJ17565_BinaryROI_tifs : binary image regions used for microarchitecture analysis17567 002 dperiod map.png : 002 d-period mapped on X-ray projection17567 002 width map.png : 002 peak width mapped on X-ray projection17567_310_Peak_D-period_data.txt : 310 d-period for each beampath through the sample17567_31