Fig. 3 in Isolation of CFTR and TMEM16A inhibitors from Neorautanenia mitis (A. Rich) Verdcourt: Potential lead compounds for treatment of secretory diarrhea

Fig. 3 in Isolation of CFTR and TMEM16A inhibitors from Neorautanenia mitis (A. Rich) Verdcourt: Potential lead compounds for treatment of secretory diarrhea

Fig. 3. Inhibitory effects of compounds 2, 6, 7 and 10 on cAMP-induced chloride secretion in T84 cells. (A) Dose response studies of compounds 2, 6, 7 and 10 on cAMP-induced chloride secretion. The representative traces of apical ISC on T84 cells are shown. (B) Data were fitted to the Hill equation...

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Hauptverfasser: Dawurung, Christiana J., Noitem, Rattikarn, Rattanajak, Roonglawan, Bunyong, Ratchanu, Richardson, Christopher, Willis, Anthony C., Kamchonwongpaisan, Sumalee, Yimnual, Chantapol, Muanprasat, Chatchai, Pyne, Stephen G.
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Sprache:eng
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Zusammenfassung:Fig. 3. Inhibitory effects of compounds 2, 6, 7 and 10 on cAMP-induced chloride secretion in T84 cells. (A) Dose response studies of compounds 2, 6, 7 and 10 on cAMP-induced chloride secretion. The representative traces of apical ISC on T84 cells are shown. (B) Data were fitted to the Hill equation and expressed as means of % forskolin-stimulated ISC ± S.E.M. (n = 3).
DOI:10.5281/zenodo.8293532