Fig. 5 in Karanjin
Fig. 5. Proposed karanjin mediated mechanism: I. Karanjin suppress TNFα production; II. Karanjin inhibits protein tyrosine phosphatase-1β (PTP-1β) which suppresses IRS-1 and activates AMPK and induces GLUT4 translocation; III. Karanjin inhibits degradation of I- κB; IV. Karanjin inhibits NF- κB tran...
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| creator | Singh, A. Bhatt, G. Gujre, N. Mitra, S. Swaminathan, R. Limaye, A.M. Rangan, L. |
| description | Fig. 5. Proposed karanjin mediated mechanism: I. Karanjin suppress TNFα production; II. Karanjin inhibits protein tyrosine phosphatase-1β (PTP-1β) which suppresses IRS-1 and activates AMPK and induces GLUT4 translocation; III. Karanjin inhibits degradation of I- κB; IV. Karanjin inhibits NF- κB translocation to nucleus; V. Karanjin suppresses ROS; VI. Induces cell cycle arrest, G2/M arrest and increase in subG1 population; VII. Karanjin induce BAX/BCL-2 ratio by inhibiting BCL-2 expression; VIII. Karanjin induce p53 expression; IX. Karanjin induces drug efflux and metabolism. |
| doi_str_mv | 10.5281/zenodo.8291572 |
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Karanjin suppress TNFα production; II. Karanjin inhibits protein tyrosine phosphatase-1β (PTP-1β) which suppresses IRS-1 and activates AMPK and induces GLUT4 translocation; III. Karanjin inhibits degradation of I- κB; IV. Karanjin inhibits NF- κB translocation to nucleus; V. Karanjin suppresses ROS; VI. Induces cell cycle arrest, G2/M arrest and increase in subG1 population; VII. Karanjin induce BAX/BCL-2 ratio by inhibiting BCL-2 expression; VIII. Karanjin induce p53 expression; IX. 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Proposed karanjin mediated mechanism: I. Karanjin suppress TNFα production; II. Karanjin inhibits protein tyrosine phosphatase-1β (PTP-1β) which suppresses IRS-1 and activates AMPK and induces GLUT4 translocation; III. Karanjin inhibits degradation of I- κB; IV. Karanjin inhibits NF- κB translocation to nucleus; V. Karanjin suppresses ROS; VI. Induces cell cycle arrest, G2/M arrest and increase in subG1 population; VII. Karanjin induce BAX/BCL-2 ratio by inhibiting BCL-2 expression; VIII. Karanjin induce p53 expression; IX. 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Proposed karanjin mediated mechanism: I. Karanjin suppress TNFα production; II. Karanjin inhibits protein tyrosine phosphatase-1β (PTP-1β) which suppresses IRS-1 and activates AMPK and induces GLUT4 translocation; III. Karanjin inhibits degradation of I- κB; IV. Karanjin inhibits NF- κB translocation to nucleus; V. Karanjin suppresses ROS; VI. Induces cell cycle arrest, G2/M arrest and increase in subG1 population; VII. Karanjin induce BAX/BCL-2 ratio by inhibiting BCL-2 expression; VIII. Karanjin induce p53 expression; IX. Karanjin induces drug efflux and metabolism.</abstract><pub>Zenodo</pub><doi>10.5281/zenodo.8291572</doi><oa>free_for_read</oa></addata></record> |
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| subjects | Biodiversity Taxonomy |
| title | Fig. 5 in Karanjin |
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