Fig. 2 in A new species of Demodex (Acari: Demodecidae) from the skin of golden-handed tamarins, Saguinus midas (Primates: Cebidae)

Fig. 2. Demodectic mange in a male golden-handed tamarin (case 1). (A) Macrophage/histiocyte accumulate and form nodules around the follicles that have filled and expanded with demodecid mites. H&E. Scale bar = 1 mm. (B) Dilated hair follicles are filled with transverse or cross sections of demodecid mites. The monotonous infiltrating macrophage/histiocyte surrounding the follicle has round to slightly irregular nuclei and abundant eosinophilic cytoplasm. Numerous mitotic figures are seen. H&E. Scale bar = 50 μm. (C) Almost all macrophage/histiocytes are strongly immunolabeled with Iba-1. Scale bar = 1 mm. (D) Numerous macrophage/histiocytes are immunolabeled for Ki-67 with a Ki-67 labeling index of 85.5%. Scale bar = 50 μm. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)