FORMULATION AND EVALUATION OF AYURVEDIC HYPERTENSION TABLET

Hypertension, a prevalent cardiovascular disorder, is often managed through conventional pharmacological interventions, which may have adverse effects. This study focuses on the development and evaluation of an ayurvedic tablet formulation for hypertension, utilizing natural ingredients renowned for their antihypertensive properties. The formulation comprises a blend of herbal extracts including Terminalia arjuna, Rauwolfia serpentina, and Withania somnifera, selected based on traditional ayurvedic texts and contemporary scientific validation. The tablets were prepared using the wet granulation method, followed by comprehensive physicochemical characterization, including hardness, friability, disintegration time, and dissolution profile. Stability studies were conducted to ensure the formulation’s shelf life. In vivo efficacy was assessed using an induced hypertensive model in rats, with blood pressure measurements taken over a specified period. The results indicated that the ayurvedic tablet formulation significantly reduced blood pressure without adverse effects, demonstrating potential as a natural alternative for hypertension management. Further clinical studies are recommended to confirm these findings and establish dosage guidelines for human use.