Dataset related to "Heterogeneous and higher-order cortical connectivity undergirds efficient, robust and reliable neural codes"

This is an accompanying dataset to the article with the title "Heterogeneous and higher-order cortical connectivity undergirds efficient, robust and reliable neural codes" (DOI: 10.1101/2024.03.15.585196). It contains structural and activity data related to the morphologically detailed mod...

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Hauptverfasser: Egas Santander, Daniela, Pokorny, Christoph, Ecker, András, Lazovskis, Jānis, Santoro, Matteo, Smith, Jason P., Hess, Kathryn, Levi, Ran, Reimann, Michael W.
Format: Dataset
Sprache:eng
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Zusammenfassung:This is an accompanying dataset to the article with the title "Heterogeneous and higher-order cortical connectivity undergirds efficient, robust and reliable neural codes" (DOI: 10.1101/2024.03.15.585196). It contains structural and activity data related to the morphologically detailed model of the rat somatosensory cortex (Markram et al., 2015), refered to as "BBP" data in the article. Specificaly, following data items are included: Simulation data: simulation.xz "Reliability" protocol: Separate folders BlobStimReliability_O1v5-SONATA_ with simulation data using the baseline and all manipulated connectomes respectively (see Technical info below), each of which containing: working_dir/connectome.h5: Connectivity matrix in ConnectivityMatrix format, which can be loaded using ConnectomeUtilities. working_dir/raw_spikes_exc_.npy: Raw (excitatory) spikes in numpy .npy format, containing an array of spike times (first column) and corresponding neuron GIDs (second column). One file for each of the 10 simulations with different simulator seeds, i.e., is 0..9. working_dir/stim_stream.npy: Stimulus train in numpy .npy format, containing the sequence of stimulus identities. working_dir/time_windows.npy: Time windows in ms in numpy .npy format, corresponding to the stimulus train. working_dir/processed_data_store.h5: Data store in HDF5 format with preprocessed spike signals (e.g., required for Gaussian kernel reliability computations), which contains... spike_signals_exc: Group of simulations datasets "sim_0" to "sim_9", each of which is an array of size and contains binned spike signals filtered with a Gaussian kernel. sigma: Sigma in ms of Gaussian kernel used for smoothing. gids: List of excitatory neuron GIDs. t_bins: List of time bins in ms. firing_rates: Average firing rates per simulation (0..9; rows) and (excitatory) neuron GID (columns); average firing rates were computed as the inverse of the mean inter-spike interval per neuron. "Classification" protocol: Single folder Toposample_O1v5-SONATA with simulation data using the baseline connectome, stored in a format compatible with the TriDy (Conceição et al., 2022) and TopoSampling (Reimann et al., 2022) pipelines, containing: toposample_input/connectivity.npz: Sparse connectivity matrix in Compressed Sparse Column format , which can be loaded using scipy.sparse.load_npz. toposample_input/neuron_info.pickle: Pandas dataframe in pickle format, which can be loaded using pandas.read_pickle, cont
DOI:10.5281/zenodo.10812496