scRNA-seq for article: Giardia intestinalis reshapes mucosal immunity toward a type-2 response that attenuates inflammatory bowel-like diseases - filtered and annotated data

Single-cell RNA-seq dataset from sorted IL-10+, TCRb+, CD4+ mouse small intestine lamina propria cells in naive or Giardia intestinalis-infected animals at 7 d.p.i. Data analyses and results are described in manuscript: "Giardia intestinalis reshapes mucosal immunity toward a Type 2 response th...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Sardinha-Silva, Aline, Gazzinelli-Guimaraes, Pedro, Ajakaye, Oluwaremilekun, Coelho, Camila, Rodrigues Ferreira, Tiago, Alves-Ferreira, Eliza, Tjhin, Erick, Gregg, Beth, Fink, Marc, Singer, Steven, Grigg, Michael
Format: Dataset
Sprache:eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Single-cell RNA-seq dataset from sorted IL-10+, TCRb+, CD4+ mouse small intestine lamina propria cells in naive or Giardia intestinalis-infected animals at 7 d.p.i. Data analyses and results are described in manuscript: "Giardia intestinalis reshapes mucosal immunity toward a Type 2 response that attenuates inflammatory bowel-like diseases". Data are Seurat objects in RDS format. Filtered-out potential doublets, low quality cells and dying cells (excluded cells with 5000 genes detected and cells with mitochondrial gene expression > 10%). Data normalization, scaling and integration performed using Seurat v 4.4.0. Full filtered dataset in the "alineGiardia.combined_v4.rds" file. T cells of interest only in the "T.seurat.rds" file.
DOI:10.5281/zenodo.10732721