MOLECULAR DYNAMIC STIMULATION – BASED PHYTOCHEMICAL SCREENING OF BUCKWHEAT (Fagopyrum esculentum) LEAF EXTRACT AGAINST CANCER BY TARGETING HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR

Fagopyrum esculentum, a member of the polygonaceae family, is commonly found in India and is known for its anticancer leaves. It is used to treat ulcers, peridontitis, anemia, constipation, and hemostasis. Fagopyrum esculentum is a complete treatment that can be used for lung cancer. Unknown is the exact chemical process that underlies buckwheat's anticancer properties. The Protein Data Bank was used to collected the crystal structure of the human epidermal growth factor receptor. Lung cancer cell growth was markedly inhibited and changed when the active components of Fagopyrum esculentum (rutin, vitexin, and quercetin) were molecularly docked with lung cancer protein. This experiment indicates that Fagopyrum esculentum can prevent lung cancer. The study's conclusions offer significant new data. KEYWORDS: Fagopyrum esculentum, Rutin,Vitexin, Quercetin and Human Epidermal Growth Factor Receptor