BALF - raw
This dataset was generated in an in vivo OECD TG 413 90-days nose-only inhalation study where Sprague Dawley rats were exposed of either aerosols of the mentholated version of the tobacco heating system 2.2 (THS2.2M) or smoke of 2 two mentholated reference cigarettes (MRC(LM) and MRC(HM)) in compari...
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| creator | Oviedo, Alberto Lebrun, Stefan Kogel, Ulrike Ho, Jenny Tan, Wey Titz, Bjoern Leroy, Patrice Vuillaume, Gregory Bera, Monali Martin, Florian Rodrigo, Gregory Esposito, Marco Dempsey, Ruth Ivanov, Nikolai Hoeng, Julia Peitsch, Manuel Vanscheeuwijck, Patrick Schlage, Walter Nury, Catherine Elamin, Ashraf Guedj, Emmanuel Trivedi, Keyur |
| description | This dataset was generated in an in vivo OECD TG 413 90-days nose-only inhalation study where Sprague Dawley rats were exposed of either aerosols of the mentholated version of the tobacco heating system 2.2 (THS2.2M) or smoke of 2 two mentholated reference cigarettes (MRC(LM) and MRC(HM)) in comparison with 3R4F cigarette smoke. Free lung cells (FLCs) in the bronchoalveolar lavage fluid were characterized and quantified by flow cytometry and BALF was characterized using targeted proteomics.
This dataset includes single measurements for each animal. |
| doi_str_mv | 10.26126/intervals.aqhyo4 |
| format | Dataset |
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This dataset includes single measurements for each animal.</description><identifier>DOI: 10.26126/intervals.aqhyo4</identifier><language>eng</language><publisher>INTERVALS</publisher><subject>Bronchoalveolar lavage fluid - BALF ; Exposure characterization ; In vivo ; Inflammation ; IQOS/THS 2.2 (PMI) ; Mentholated Reference Cigarette ; R4F ; Rat ; Respiratory disease</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>780,1894</link.rule.ids><linktorsrc>$$Uhttps://commons.datacite.org/doi.org/10.26126/intervals.aqhyo4$$EView_record_in_DataCite.org$$FView_record_in_$$GDataCite.org$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Oviedo, Alberto</creatorcontrib><creatorcontrib>Lebrun, Stefan</creatorcontrib><creatorcontrib>Kogel, Ulrike</creatorcontrib><creatorcontrib>Ho, Jenny</creatorcontrib><creatorcontrib>Tan, Wey</creatorcontrib><creatorcontrib>Titz, Bjoern</creatorcontrib><creatorcontrib>Leroy, Patrice</creatorcontrib><creatorcontrib>Vuillaume, Gregory</creatorcontrib><creatorcontrib>Bera, Monali</creatorcontrib><creatorcontrib>Martin, Florian</creatorcontrib><creatorcontrib>Rodrigo, Gregory</creatorcontrib><creatorcontrib>Esposito, Marco</creatorcontrib><creatorcontrib>Dempsey, Ruth</creatorcontrib><creatorcontrib>Ivanov, Nikolai</creatorcontrib><creatorcontrib>Hoeng, Julia</creatorcontrib><creatorcontrib>Peitsch, Manuel</creatorcontrib><creatorcontrib>Vanscheeuwijck, Patrick</creatorcontrib><creatorcontrib>Schlage, Walter</creatorcontrib><creatorcontrib>Nury, Catherine</creatorcontrib><creatorcontrib>Elamin, Ashraf</creatorcontrib><creatorcontrib>Guedj, Emmanuel</creatorcontrib><creatorcontrib>Trivedi, Keyur</creatorcontrib><title>BALF - raw</title><description>This dataset was generated in an in vivo OECD TG 413 90-days nose-only inhalation study where Sprague Dawley rats were exposed of either aerosols of the mentholated version of the tobacco heating system 2.2 (THS2.2M) or smoke of 2 two mentholated reference cigarettes (MRC(LM) and MRC(HM)) in comparison with 3R4F cigarette smoke. Free lung cells (FLCs) in the bronchoalveolar lavage fluid were characterized and quantified by flow cytometry and BALF was characterized using targeted proteomics.
This dataset includes single measurements for each animal.</description><subject>Bronchoalveolar lavage fluid - BALF</subject><subject>Exposure characterization</subject><subject>In vivo</subject><subject>Inflammation</subject><subject>IQOS/THS 2.2 (PMI)</subject><subject>Mentholated Reference Cigarette</subject><subject>R4F</subject><subject>Rat</subject><subject>Respiratory disease</subject><fulltext>true</fulltext><rsrctype>dataset</rsrctype><creationdate>2023</creationdate><recordtype>dataset</recordtype><sourceid>PQ8</sourceid><recordid>eNpjYJA0NNAzMjM0MtPPzCtJLSpLzCnWSyzMqMw34WTgcnL0cVPQVShKLOdhYE0DSqXyQmluBkM31xBnD92UxJLE5MyS1PiCoszcxKLKeEODeLB58XDz4iHmGZOjBwDqLjK1</recordid><startdate>20230613</startdate><enddate>20230613</enddate><creator>Oviedo, Alberto</creator><creator>Lebrun, Stefan</creator><creator>Kogel, Ulrike</creator><creator>Ho, Jenny</creator><creator>Tan, Wey</creator><creator>Titz, Bjoern</creator><creator>Leroy, Patrice</creator><creator>Vuillaume, Gregory</creator><creator>Bera, Monali</creator><creator>Martin, Florian</creator><creator>Rodrigo, Gregory</creator><creator>Esposito, Marco</creator><creator>Dempsey, Ruth</creator><creator>Ivanov, Nikolai</creator><creator>Hoeng, Julia</creator><creator>Peitsch, Manuel</creator><creator>Vanscheeuwijck, Patrick</creator><creator>Schlage, Walter</creator><creator>Nury, Catherine</creator><creator>Elamin, Ashraf</creator><creator>Guedj, Emmanuel</creator><creator>Trivedi, Keyur</creator><general>INTERVALS</general><scope>DYCCY</scope><scope>PQ8</scope></search><sort><creationdate>20230613</creationdate><title>BALF - raw</title><author>Oviedo, Alberto ; Lebrun, Stefan ; Kogel, Ulrike ; Ho, Jenny ; Tan, Wey ; Titz, Bjoern ; Leroy, Patrice ; Vuillaume, Gregory ; Bera, Monali ; Martin, Florian ; Rodrigo, Gregory ; Esposito, Marco ; Dempsey, Ruth ; Ivanov, Nikolai ; Hoeng, Julia ; Peitsch, Manuel ; Vanscheeuwijck, Patrick ; Schlage, Walter ; Nury, Catherine ; Elamin, Ashraf ; Guedj, Emmanuel ; Trivedi, Keyur</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-datacite_primary_10_26126_intervals_aqhyo43</frbrgroupid><rsrctype>datasets</rsrctype><prefilter>datasets</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Bronchoalveolar lavage fluid - BALF</topic><topic>Exposure characterization</topic><topic>In vivo</topic><topic>Inflammation</topic><topic>IQOS/THS 2.2 (PMI)</topic><topic>Mentholated Reference Cigarette</topic><topic>R4F</topic><topic>Rat</topic><topic>Respiratory disease</topic><toplevel>online_resources</toplevel><creatorcontrib>Oviedo, Alberto</creatorcontrib><creatorcontrib>Lebrun, Stefan</creatorcontrib><creatorcontrib>Kogel, Ulrike</creatorcontrib><creatorcontrib>Ho, Jenny</creatorcontrib><creatorcontrib>Tan, Wey</creatorcontrib><creatorcontrib>Titz, Bjoern</creatorcontrib><creatorcontrib>Leroy, Patrice</creatorcontrib><creatorcontrib>Vuillaume, Gregory</creatorcontrib><creatorcontrib>Bera, Monali</creatorcontrib><creatorcontrib>Martin, Florian</creatorcontrib><creatorcontrib>Rodrigo, Gregory</creatorcontrib><creatorcontrib>Esposito, Marco</creatorcontrib><creatorcontrib>Dempsey, Ruth</creatorcontrib><creatorcontrib>Ivanov, Nikolai</creatorcontrib><creatorcontrib>Hoeng, Julia</creatorcontrib><creatorcontrib>Peitsch, Manuel</creatorcontrib><creatorcontrib>Vanscheeuwijck, Patrick</creatorcontrib><creatorcontrib>Schlage, Walter</creatorcontrib><creatorcontrib>Nury, Catherine</creatorcontrib><creatorcontrib>Elamin, Ashraf</creatorcontrib><creatorcontrib>Guedj, Emmanuel</creatorcontrib><creatorcontrib>Trivedi, Keyur</creatorcontrib><collection>DataCite (Open Access)</collection><collection>DataCite</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Oviedo, Alberto</au><au>Lebrun, Stefan</au><au>Kogel, Ulrike</au><au>Ho, Jenny</au><au>Tan, Wey</au><au>Titz, Bjoern</au><au>Leroy, Patrice</au><au>Vuillaume, Gregory</au><au>Bera, Monali</au><au>Martin, Florian</au><au>Rodrigo, Gregory</au><au>Esposito, Marco</au><au>Dempsey, Ruth</au><au>Ivanov, Nikolai</au><au>Hoeng, Julia</au><au>Peitsch, Manuel</au><au>Vanscheeuwijck, Patrick</au><au>Schlage, Walter</au><au>Nury, Catherine</au><au>Elamin, Ashraf</au><au>Guedj, Emmanuel</au><au>Trivedi, Keyur</au><format>book</format><genre>unknown</genre><ristype>DATA</ristype><title>BALF - raw</title><date>2023-06-13</date><risdate>2023</risdate><abstract>This dataset was generated in an in vivo OECD TG 413 90-days nose-only inhalation study where Sprague Dawley rats were exposed of either aerosols of the mentholated version of the tobacco heating system 2.2 (THS2.2M) or smoke of 2 two mentholated reference cigarettes (MRC(LM) and MRC(HM)) in comparison with 3R4F cigarette smoke. Free lung cells (FLCs) in the bronchoalveolar lavage fluid were characterized and quantified by flow cytometry and BALF was characterized using targeted proteomics.
This dataset includes single measurements for each animal.</abstract><pub>INTERVALS</pub><doi>10.26126/intervals.aqhyo4</doi><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | DOI: 10.26126/intervals.aqhyo4 |
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| language | eng |
| recordid | cdi_datacite_primary_10_26126_intervals_aqhyo4 |
| source | DataCite |
| subjects | Bronchoalveolar lavage fluid - BALF Exposure characterization In vivo Inflammation IQOS/THS 2.2 (PMI) Mentholated Reference Cigarette R4F Rat Respiratory disease |
| title | BALF - raw |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-06T17%3A11%3A01IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-datacite_PQ8&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=unknown&rft.au=Oviedo,%20Alberto&rft.date=2023-06-13&rft_id=info:doi/10.26126/intervals.aqhyo4&rft_dat=%3Cdatacite_PQ8%3E10_26126_intervals_aqhyo4%3C/datacite_PQ8%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |