Proteomics raw data of mammary tumor cells from female dogs

This data is part of the material used to study the effect of rapamycin on mammary tumor cells of female dogs. We would like to evaluate the dose response of mammary tumor cells from dogs and evaluate the proteins comparing before and after treatment with rapamycin. We used samples of tumors from ma...

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1. Verfasser: De Faria Lainetti, Patrícia
Format: Dataset
Sprache:eng
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Zusammenfassung:This data is part of the material used to study the effect of rapamycin on mammary tumor cells of female dogs. We would like to evaluate the dose response of mammary tumor cells from dogs and evaluate the proteins comparing before and after treatment with rapamycin. We used samples of tumors from mammary gland and their respective metastases from 2 animals. Four samples were cultured in vitro and treated with rapamycin in different doses (IC50) for each cell line. The cells were prepared to proteomics (ESI Q-TOF MS/MS). We used for statistical analysis comparisons between control versus rapamycin treatment groups, and also metastasis versus primary tumor versus metastasis rapamycin versus primary tumor rapamycin. The experiment was performed in biological duplicates and in technical duplicates.
DOI:10.17632/y69wn559ym