A microbial derived bile acid acts as GPBAR1 agonist and RORγt inverse agonist and reverses inflammation in inflammatory bowel disease - Bile acids quantification through UHPLC-MRM-MS section

The interplay between the gut microbiota, bile acids and the immune is a critical determinant in development of inflammatory bowel disease (IBD). Here we investigated the fecal bile acid profiles in murine models of colitis, through UHPLC-MRM-MS.

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1. Verfasser: Morretta, Elva
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Sprache:eng
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Zusammenfassung:The interplay between the gut microbiota, bile acids and the immune is a critical determinant in development of inflammatory bowel disease (IBD). Here we investigated the fecal bile acid profiles in murine models of colitis, through UHPLC-MRM-MS.
DOI:10.17632/hmkvmsxrmb