Lipids, biomarkers, and subclinical atherosclerosis in treatment-naive HIV patients starting or not starting antiretroviral therapy : Comparison with a healthy control group in a 2-year prospective study

To assess the effect of HIV infection and combined antiretroviral therapy (c-ART) on various proatherogenic biomarkers and lipids and to investigate their relationship with subclinical atherosclerosis in a cohort of treatment-naive HIV-infected patients. We performed a prospective, comparative, mult...

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Hauptverfasser: Di Yacovo, Silvana, Saumoy, Maria, Sanchez-Quesada, Jose Luis, Navarro, Antonio, Sviridov, Dmitri, Javaloyas, Manuel, Vila, Ramon, Vernet, Anton, Low, Hann, Peñafiel, Judith, García, Benito, Ordoñez Llanos, Jorge, Podzamczer, Daniel, Universitat Autònoma de Barcelona
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Sprache:eng
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Zusammenfassung:To assess the effect of HIV infection and combined antiretroviral therapy (c-ART) on various proatherogenic biomarkers and lipids and to investigate their relationship with subclinical atherosclerosis in a cohort of treatment-naive HIV-infected patients. We performed a prospective, comparative, multicenter study of 2 groups of treatment-naive HIV-infected patients (group A, CD4>500 cells/μL, not starting c-ART; and group B, CD4