Imputation method to reduce undetected severe acute respiratory infection cases during the coronavirus disease outbreak in Brazil

Imputation method to reduce undetected severe acute respiratory infection cases during the coronavirus disease outbreak in Brazil

The coronavirus disease (COVD-19) outbreak has overburdened the surveillance of severe acute respiratory infections (SARIs), including the laboratory network. This study was aimed at correcting the absence of laboratory results of reported SARI deaths. The imputation method was applied for SARI deat...

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Bibliographische Detailangaben
Hauptverfasser: de Oliveira, Silvano Barbosa, Ganem dos Santos, Fabiana Sherine, de Araújo, Wildo Navegantes, Casabona-Barbarà, Jordi, Sanchez, Mauro Niskier, Croda, Julio
Format: Artikel
Sprache:eng
Schlagworte:
COVID-19
Imputation method
Laboratory test
SARI
Signs and symptoms
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Zusammenfassung:The coronavirus disease (COVD-19) outbreak has overburdened the surveillance of severe acute respiratory infections (SARIs), including the laboratory network. This study was aimed at correcting the absence of laboratory results of reported SARI deaths. The imputation method was applied for SARI deaths without laboratory information using clinico-epidemiological characteristics. Of 84,449 SARI deaths, 51% were confirmed with COVID-19 while 3% with other viral respiratory diseases. After the imputation method, 95% of deaths were reclassified as COVID-19 while 5% as other viral respiratory diseases. The imputation method was a useful and robust solution (sensitivity and positive predictive value of 98%) for missing values through clinical & epidemiological characteristics.