From transformation to chronification of migraine : pathophysiological and clinical aspects

From transformation to chronification of migraine : pathophysiological and clinical aspects

Chronic migraine is a neurological disorder characterized by 15 or more headache days per month of which at least 8 days show typical migraine features. The process that describes the development from episodic migraine into chronic migraine is commonly referred to as migraine transformation or chron...

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Hauptverfasser: Torres-Ferrús, M, Ursitti, F, Alpuente, Alicia, Brunello, F, Chiappino, D, de Vries, T, Di Marco, S, Ferlisi, S, Guerritore, L, Gonzalez-Garcia, N, Gonzalez-Martinez, A, Khutorov, D, Kritsilis, M, Kyrou, A, Makeeva, T, Minguez-Olaondo, A, Pilati, L, Serrien, A, Tsurkalenko, O, Van den Abbeele, D, van Hoogstraten, W. S, Lampl, Christian, Universitat Autònoma de Barcelona, Universitat Autònoma de Barcelona. Vall d'Hebron Institut de Recerca (VHIR)
Format: Artikel
Sprache:eng
Schlagworte:
Animal models
Biomarker
Chronic migraine
Genetics
Neuroimaging
Neurophysiology
Pathophysiology
Risk factors
Transformation
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Zusammenfassung:Chronic migraine is a neurological disorder characterized by 15 or more headache days per month of which at least 8 days show typical migraine features. The process that describes the development from episodic migraine into chronic migraine is commonly referred to as migraine transformation or chronification. Ample studies have attempted to identify factors associated with migraine transformation from different perspectives. Understanding CM as a pathological brain state with trigeminovascular participation where biological changes occur, we have completed a comprehensive review on the clinical, epidemiological, genetic, molecular, structural, functional, physiological and preclinical evidence available.