Total Synthesis of Aeruginazole A

The first total synthesis of Aeruginazole A, prepared via a convergent strategy that involved both solid-phase peptide synthesis and solution phase chemistry and that enabled conservation of the stereochemistry of the intermediates, is reported.

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Organic letters 2011-09, Vol.13 (17), p.4648-4651
Hauptverfasser:	Bruno, Paolo, Peña, Stella, Just-Baringo, Xavier, Albericio, Fernando, Álvarez, Mercedes
Format:	Artikel
Sprache:	eng
Schlagworte:	Heterocyclic chemistry Molecular Conformation Peptide synthesis Peptides, Cyclic - chemical synthesis Peptides, Cyclic - chemistry Química heterocíclica Stereoisomerism Síntesi de pèptids Thiazoles - chemical synthesis Thiazoles - chemistry
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The first total synthesis of Aeruginazole A, prepared via a convergent strategy that involved both solid-phase peptide synthesis and solution phase chemistry and that enabled conservation of the stereochemistry of the intermediates, is reported.
ISSN:	1523-7060 1523-7052
DOI:	10.1021/ol2018592