Lipid Abnormalities among Libyan HIV-Infected Patients Receiving Antiretroviral (ARV) Drugs and ARV Naïve Patients

Introduction: Majority of untreated or Anti-Retroviral (ARV) treated HIV subjects may experience a lot of metabolic alterations including dyslipidemia, lipodystrophy and insulin resistance. Aim: Due to the shortage of research data related to HIV infection. We conducted this study to assess the lipid profile in HIV infected subjects and to find a correlation between liver function enzymes and other biomarkers and serum lipid alterations among Libyan HIV subjects. Materials and Methods: Case control study included 121 Libyan HIV-1 positive subjects (101 subjects were on First-line ARV treatment regimens and 21 untreated "Naïve") from Benghazi Medical Center (BMC) and Benghazi center for infectious diseases and immunology (BCIDI) during 2018-2019 to evaluate lipid profile and other biochemical parameters. Control group included 70 age-matched HIV negative individuals. The age range of the study participants was 20-45 years. Results: The means of CD4 count in the ARV treated HIV subjects were significantly (P