Diving Deep into Diagnosis: Unveiling Section High Grade B-cell Lymphoma

The term “lymphoma” comprises a heterogeneous group of biologically and clinically distinct neoplasms that arise from cells in the lymphoid organs. Based on the identification of Reed-Sternberg cells (RS cells), it is divided into Hodgkin and NonHodgkin’s Lymphoma (NHL). Lymphadenopathy is a common...

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Veröffentlicht in:Journal of clinical and diagnostic research 2024
Hauptverfasser: Mahashabde, Madhulika Laxmikant, Bhimani, Yash Rameshbhai, Chaudhary, Gaurav Ashok
Format: Artikel
Sprache:eng
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Zusammenfassung:The term “lymphoma” comprises a heterogeneous group of biologically and clinically distinct neoplasms that arise from cells in the lymphoid organs. Based on the identification of Reed-Sternberg cells (RS cells), it is divided into Hodgkin and NonHodgkin’s Lymphoma (NHL). Lymphadenopathy is a common presenting feature of lymphoma. Extranodal involvement may show gastrointestinal, cutaneous, neurological, or other symptoms. Hereby, the authors present a case report of 76-year-old male with non-Hodgkin’s lymphoma whose symptoms were masked by the abdominal pain of emphysematous pyelonephritis. Although the infection was treated, the patient continued to complain of dull, aching, persistent abdominal pain. As a result, the patient underwent additional radiological examinations, including a contrast-enhanced Computed Tomography (CT) scan of the abdomenpelvis, which disclosed multiple lymphadenopathies. Hence, an endoscopic ultrasound-guided biopsy was performed from the lymph node between the portal vein and inferior vena cava, revealed High-grade B-cell Lymphoma (HGBL). The prognosis for HGBL with double- and triple-hit lymphomas is extremely bad. The patient that came to us had an early diagnosis of HGBL, which led to a favourable prognosis, in contrast to most cases of the disease, which usually manifest late in the course and are linked with a very grave prognosis.
ISSN:2249-782X
DOI:10.7860/JCDR/2024/73273.19735