Pyloricidins, Novel Anti-Helicobacter pylori Antibiotics Produced by Bacillus sp: I. Taxonomy, Fermentation and Biological Activity
Novel anti-Helicobacter pylori antibiotics, pyloricidins A, A1, A2, B, C and D, were discovered in the culture broth of two bacilli strains. Pyloricidins selectively inhibited the growth of H. pylori. Pyloricidin B was efficacious in the treatment of gastric infection caused by H. pylori in Mongolia...
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| Veröffentlicht in: | Journal of antibiotics 2001/11/25, Vol.54(11), pp.926-933 |
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| container_end_page | 933 |
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| container_issue | 11 |
| container_start_page | 926 |
| container_title | Journal of antibiotics |
| container_volume | 54 |
| creator | NAKAO, MASAFUMI MIYAGAWA, KEN-ICHIRO NAKANO, YOSHITAKA SAKANE, TAKESHI TADA, MAYUMI NISHIMURA, OSAMU FUJINO, MASAHIKO |
| description | Novel anti-Helicobacter pylori antibiotics, pyloricidins A, A1, A2, B, C and D, were discovered in the culture broth of two bacilli strains. Pyloricidins selectively inhibited the growth of H. pylori. Pyloricidin B was efficacious in the treatment of gastric infection caused by H. pylori in Mongolian gerbils and may be promising for cure of H, pylori infection as a single agent. |
| doi_str_mv | 10.7164/antibiotics.54.926 |
| format | Article |
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Drug treatments</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>NAKAO, MASAFUMI</creatorcontrib><creatorcontrib>MIYAGAWA, KEN-ICHIRO</creatorcontrib><creatorcontrib>NAKANO, YOSHITAKA</creatorcontrib><creatorcontrib>SAKANE, TAKESHI</creatorcontrib><creatorcontrib>TADA, MAYUMI</creatorcontrib><creatorcontrib>NISHIMURA, OSAMU</creatorcontrib><creatorcontrib>FUJINO, MASAHIKO</creatorcontrib><collection>Pascal-Francis</collection><collection>CrossRef</collection><jtitle>Journal of antibiotics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>NAKAO, MASAFUMI</au><au>MIYAGAWA, KEN-ICHIRO</au><au>NAKANO, YOSHITAKA</au><au>SAKANE, TAKESHI</au><au>TADA, MAYUMI</au><au>NISHIMURA, OSAMU</au><au>FUJINO, MASAHIKO</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pyloricidins, Novel Anti-Helicobacter pylori Antibiotics Produced by Bacillus sp: I. Taxonomy, Fermentation and Biological Activity</atitle><jtitle>Journal of antibiotics</jtitle><addtitle>J. Antibiot.</addtitle><date>2001</date><risdate>2001</risdate><volume>54</volume><issue>11</issue><spage>926</spage><epage>933</epage><pages>926-933</pages><issn>0021-8820</issn><eissn>1881-1469</eissn><coden>JANTAJ</coden><abstract>Novel anti-Helicobacter pylori antibiotics, pyloricidins A, A1, A2, B, C and D, were discovered in the culture broth of two bacilli strains. Pyloricidins selectively inhibited the growth of H. pylori. Pyloricidin B was efficacious in the treatment of gastric infection caused by H. pylori in Mongolian gerbils and may be promising for cure of H, pylori infection as a single agent.</abstract><cop>Tokyo</cop><pub>JAPAN ANTIBIOTICS RESEARCH ASSOCIATION</pub><doi>10.7164/antibiotics.54.926</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 0021-8820 |
| ispartof | The Journal of Antibiotics, 2001/11/25, Vol.54(11), pp.926-933 |
| issn | 0021-8820 1881-1469 |
| language | eng |
| recordid | cdi_crossref_primary_10_7164_antibiotics_54_926 |
| source | J-STAGE (Japan Science & Technology Information Aggregator, Electronic) Freely Available Titles - Japanese |
| subjects | Antibacterial agents Antibiotics (antibacterial agents, antifungal agents) Antibiotics, microbial producers, chemotherapic agents, antiseptics, disinfecting agents Antibiotics. Antiinfectious agents. Antiparasitic agents Applied microbiology Biological and medical sciences Fundamental and applied biological sciences. Psychology Medical sciences Microbiology Pharmacology. Drug treatments |
| title | Pyloricidins, Novel Anti-Helicobacter pylori Antibiotics Produced by Bacillus sp: I. Taxonomy, Fermentation and Biological Activity |
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