THE PRODUCER AND BIOLOGICAL ACTIVITIES OF SO-075R1, A NEW MUTACTIMYCIN GROUP ANTIBIOTIC

THE PRODUCER AND BIOLOGICAL ACTIVITIES OF SO-075R1, A NEW MUTACTIMYCIN GROUP ANTIBIOTIC

The producer of SO-075R1, a new anthracycline group antibiotic was identified as Nocardia brasiliensis. SO-075R1 was active against Gram-positive bacteria, but not active against Gram-negative bacteria or fungi. All tested Nocardia brasiliensis strains as well as the producer itself were resistant t...

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Veröffentlicht in:Journal of antibiotics 1992/12/25, Vol.45(12), pp.1848-1852
Hauptverfasser: MAEDA, AKIO, YAZAWA, KATSUKIYO, MIKAMI, YUZURU, ISHIBASHI, MASASHI, KOBAYASHI, JUN'ICHI
Format: Artikel
Sprache:eng
Schlagworte:
Antineoplastic agents
Biological and medical sciences
General aspects
Medical sciences
Pharmacology. Drug treatments
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Beschreibung
Zusammenfassung:The producer of SO-075R1, a new anthracycline group antibiotic was identified as Nocardia brasiliensis. SO-075R1 was active against Gram-positive bacteria, but not active against Gram-negative bacteria or fungi. All tested Nocardia brasiliensis strains as well as the producer itself were resistant to SO-075R1, although four other pathogenic Nocardia, i.e. N. asteroides, N. nova, N. farcinica and N. otitidiscaviarum were sensitive.
ISSN:0021-8820
1881-1469
DOI:10.7164/antibiotics.45.1848