G7063-2, A NEW NITROGEN-CONTAINING ANTIBIOTIC OF THE EPOXYDON GROUP, ISOLATED FROM THE FERMENTATION BROTH OF A SPECIES OF STREPTOMYCES

Antibiotic G7063-2, isolated from a Streptomyces species, is a new nitrogen-containing analogue of phyllostine and terreic acid. In vitro G7063-2 is moderately active against both Gram-positive and Gram-negative bacteria and weakly active against fungi. It is toxic to mice.

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of antibiotics 1977, Vol.30(6), pp.455-459
Hauptverfasser:	NOBLE, MARY, NOBLE, D., SYKES, R. B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Bacterial Agents - isolation & purification Anti-Bacterial Agents - pharmacology Anti-Bacterial Agents - toxicity Bacteria - drug effects Chemical Phenomena Chemistry Chromatography, Thin Layer Culture Media - analysis Female Fermentation Fungi - drug effects Lethal Dose 50 Mass Spectrometry Mice Streptomyces - metabolism
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Beschreibung
Zusammenfassung:	Antibiotic G7063-2, isolated from a Streptomyces species, is a new nitrogen-containing analogue of phyllostine and terreic acid. In vitro G7063-2 is moderately active against both Gram-positive and Gram-negative bacteria and weakly active against fungi. It is toxic to mice.
ISSN:	0021-8820 1881-1469
DOI:	10.7164/antibiotics.30.455