Anticoagulant Therapy of the Soleal Vein Thrombosis: Changes of Local Thrombi and Alterations of Right Heart Load

Changes of local thrombi and alterations of right heart load by the anticoagulant therapy were investigated in the patients with soleal vein thrombosis (SVT) and crural vein thrombosis (CVT). The subjects were 24 in the SVT and 21 in the CVT. In the changes of local thrombi, the effective rate of disappearance and decrease in size was 63% and was not significant between the SVT and the CVT. In the alterations of right heart load, the right heart systolic pressure decreased significantly. The rates of the patients with pulmonary hypertension more than 40 mmHg were significantly reduced in both SVT and CVT, and the rate of the patients with right ventricle load more than 30 mmHg was significantly reduced in the SVT. Anticoagulant therapy could give more extensive reduction of the right heart load to the patients with SVT than those with CVT.