A conceptual review of Madhumeha according to Ayurveda and contemporary science

Diabetes Mellitus (Madhumeha) is a group of metabolic diseases associated with hyperglycemia which is due to absolute deficiency of insulin or diminished biological effectiveness of it characterized by polyuria, polyphagia and polydipsia. It is a single most important metabolic disorder that affects almost every organ/system in the body. In Ayurveda, acharyas have mentioned disease according to the strotasas involved and these diseases are classified according to the Dosha predominance. Out of the four types of Vataj prameha, Madhumeha is one of the type. It is a common chronic metabolic disease which is correlated with Diabetes Mellitus. Diabetes Mellitus is prevalent all over the world with an alarming rise in its prevalence day by day. As per Indian Council of Medical Research – India Diabetes (ICMR INDIAB) study published in 2023, the prevalence of diabetes is 10.1 crore. By 2030, 643 million people will have diabetes globally, increasing to 783 million by 2045. The management of Madhumeha is considered as a global problem. Thus the study has been done to get through the depths of all the insights about the pathogenesis of disease according to both modern as well as ayurved literature which would later prove helpful to precisely establish the curability of disease and to acknowledge the limitations of treatment.