Mutagenicity of Chlorinated Aromatic Hydrocarbons containing Oxygen

Mutagenicity of twenty seven chlorinated aromatic hydrocarbons containing oxygen in their molecules were examined using preincubation method employingSalmonella typhimuyiumTA100, TA98, TA104 andEscherichia coliWP2uvrA/pKM101 with and without metabolic activation (S9mix) . Chlorobenzoic acids, chloro...

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Veröffentlicht in:	Journal of Environmental Chemistry 1996/12/16, Vol.6(4), pp.533-540
Hauptverfasser:	OHKUBO, Tadamichi, GOTO, Sumio, ENDO, Osamu, HAYASHI, Tetsuhito, WATANABE, Etsuo, ENDO, Hideaki
Format:	Artikel
Sprache:	eng
Schlagworte:	chlorinated aromatic hydrocarbon Escherichia coli WP2uvrA/pKM101 mutagenicity Salmonella typhimurium TA104
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description	Mutagenicity of twenty seven chlorinated aromatic hydrocarbons containing oxygen in their molecules were examined using preincubation method employingSalmonella typhimuyiumTA100, TA98, TA104 andEscherichia coliWP2uvrA/pKM101 with and without metabolic activation (S9mix) . Chlorobenzoic acids, chlorobenzaldehydes, and chlorophenylacetic acids showed no mutagenicity under any conditions. Positive results were given in 13 chloride compounds, e.g., benzoyl chloride, with TA100 (0.8-2.7rev./μg) and TA104 (1.0-3.3rev./μg) with S9mix.
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Chlorobenzoic acids, chlorobenzaldehydes, and chlorophenylacetic acids showed no mutagenicity under any conditions. 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Chlorobenzoic acids, chlorobenzaldehydes, and chlorophenylacetic acids showed no mutagenicity under any conditions. Positive results were given in 13 chloride compounds, e.g., benzoyl chloride, with TA100 (0.8-2.7rev./μg) and TA104 (1.0-3.3rev./μg) with S9mix.</abstract><pub>Japan Society for Environmental Chemistry</pub><doi>10.5985/jec.6.533</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record>
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subjects	chlorinated aromatic hydrocarbon Escherichia coli WP2uvrA/pKM101 mutagenicity Salmonella typhimurium TA104
title	Mutagenicity of Chlorinated Aromatic Hydrocarbons containing Oxygen
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