A Measurement Method of Uptakes for Volatile Chlorinated Hydrocarbons to Respiratory Organs

The uptakes of five volatile chlorinated hydrocarbons (VCHs) into respiratory organs were evaluated at similar concentrations to those in environmental air. Trichloroethylene (TRI), 1, 1, 1-trichloroethane (111TRI), tetrachloroethylene (PERC), tetrachloromethane (TCM), and chloroform (CHLO), in n-hexane solution were vaporized in an office (68m3) . Then, the room air as inhaled air and exhaled air from a volunteer were simultaneously collected with 2L and 1L of Tedlar Bags, respectively, at several time-intervals. All samples were directly analyzed by GC/ECD. The concentration of each of VCHs in both inhaled air and exhaled air was measured as a function of the sampling time, and the time -average uptake of each of VCHs into respiratory organs was evaluated: TRI, 50.6±5.8%; CHLO, 47.7±5.9%; PERC, 38.6±10.8%; TCM, 24.8±10.4%; 111TRI, 19.8±7.7%.